| カタログ番号 | HY286096 |
| 宿主種 | Humanized |
| 種反応性 | Human |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS, pH 7.4. |
| 純度 | >95% purity as determined by SDS-PAGE. |
| クローン性 | Monoclonal |
| アイソタイプ | IgG1-kappa |
| アプリケーション | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| ターゲット | p185erbB2, HER2, NGL, Tyrosine kinase-type cell surface receptor HER2, NEU, MLN 19, Proto-oncogene Neu, MLN19, ERBB2, Proto-oncogene c-ErbB-2, CD340, Receptor tyrosine-protein kinase erbB-2, Metastatic lymph node gene 19 protein, ERBB3, HER3, Proto-oncogene-like protein c-ErbB-3, Tyrosine kinase-type cell surface receptor HER3, Receptor tyrosine-protein kinase erbB-3 |
| 精製 | Protein A/G purified from cell culture supernatant. |
| エンドトキシンレベル | Please contact the lab for this information. |
| 発現システム | Mammalian Cells |
| アクセッション番号 | P04626 & P21860 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternative name | Bispecific, MCLA-128, PB4188, R040517, 1969309-56-5 |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
Research Grade Zenocutuzumab
概要
説明
Zenocutuzumab (HY286096) is a research-grade recombinant antibody targeting CD340. Produced in mammalian cells with native-like glycosylation.
Highlights
- ●Research Grade — For PK/PD studies, assay development, and ADA research.
- ●Native Glycosylation — Mammalian expression ensures native-like patterns.
イメージ
 Bioactivity |
Detects CD340/ERBB2/HER2/NEU in indirect ELISAs. |
 SDS-PAGE |
SDS-PAGE for Research Grade Zenocutuzumab |
 Flow CytoMetry |
Flow-cytometry using anti-human ERBB3 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human ERBB3 monoclonal antibody (Catalog: HY286096) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer. |
 Western blot |
Western blot analysis was performed using anti-CD340/ERBB2 monoclonal antibody at 1μg/ml on various samples. Lane 1: recombinant human CD340/ERBB2 (Catalog No: HY286011) |