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Research Grade Bococizumab
Aperçu
Numéro de catalogue HV275046
Espèce hôte Humanized
Reactivité des espèces Human
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4.
Pureté >95% purity as determined by SDS-PAGE.
Clonalité Monoclonal
Isotype IgG2-kappa
Applications ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Cible Proprotein convertase subtilisin/kexin type 9, Subtilisin/kexin-like protease PC9, NARC-1, PC9, Proprotein convertase 9, Neural apoptosis-regulated convertase 1, NARC1, PCSK9
Purification Protein A/G purified from cell culture supernatant.
Niveau d'endotoxines Please contact the lab for this information.
Système d'expression Mammalian Cells
Numéro d'accès Q8NBP7
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternative name PF-04950615, RN-316, 1407495-02-6
Note For research use only. Not suitable for clinical or therapeutic use.
Description

Bococizumab (HV275046) is a research-grade recombinant antibody targeting Proprotein convertase subtilisin/kexin type 9. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.

Images


SDS-PAGE
SDS-PAGE for Research Grade Bococizumab

Bioactivity
SEC-HPLC detection for Research Grade Bococizumab.

Bioactivity
Detects Human PCSK9 in indirect ELISAs.
Immobilized Human PCSK9, His Tag (Catalog No: HV275011) at 1 μg/mL (100 μL/well) on an Anti-His antibody (Catalog No: YP205015) Coated plate can bind Human PCSK9 Mab