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Research Grade Landogrozumab
Overview
Catalog No. HT343016
Host species Humanized
Species reactivity Human
Form Liquid
Storage buffer 0.01M PBS, pH 7.4.
Purity >95% purity as determined by SDS-PAGE.
Clonality Monoclonal
Isotype IgG4-kappa
Applications ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Target GDF-8, GDF8, MSTN, Myostatin, Growth/differentiation factor 8
Purification Protein A/G purified from cell culture supernatant.
Endotoxin level Please contact the lab for this information.
Expression system Mammalian Cells
Accession O14793
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternative nameLY-2495655, 1391726-30-9
Note For research use only. Not suitable for clinical or therapeutic use.
Images


Bioactivity
SEC-HPLC detection for Research Grade Landogrozumab.

Flow Cytometry
Flow-cytometry using anti-human MSTN antibody. LNCAP cells were fixed and permeabilized, then stained with an irrelevant antibody (Blue Histogram) or an anti-human MSTN monoclonal antibody (Catalog HT343016, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.

SDS-PAGE
SDS-PAGE for Research Grade Landogrozumab.