| Catalog No. | HV275016 |
| Host species | Human |
| Species reactivity | Human |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Clonality | Monoclonal |
| Isotype | IgG1-kappa |
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Target | Proprotein convertase subtilisin/kexin type 9, Subtilisin/kexin-like protease PC9, NARC-1, PC9, Proprotein convertase 9, Neural apoptosis-regulated convertase 1, NARC1, PCSK9 |
| Purification | Protein A/G purified from cell culture supernatant. |
| Endotoxin level | Please contact the lab for this information. |
| Expression system | Mammalian Cells |
| Accession | Q8NBP7 |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternative name | REGN727, SAR-236553, 1245916-14-6 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
Research Grade Alirocumab
Overview
Images
 Flow Cytometry |
Flow-cytometry using anti-human PCSK9 antibody. Jurkat cells were fixed and permeabilized, then stained with an irrelevant antibody (Blue Histogram) or an anti-human PCSK9 monoclonal antibody (Catalog HV275016, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer. |
 SDS-PAGE |
SDS-PAGE for Research Grade Alirocumab. |
 Bioactivity |
Detects Human PCSK9 in indirect ELISAs. Immobilized Human PCSK9, His Tag (Catalog No: HV275011) at 1 μg/mL (100 μL/well) on an Anti-His antibody (Catalog No: YP205015) Coated plate can bind Human PCSK9 Mab |