| Catalog No. | HV612046 |
| Host species | Humanized |
| Species reactivity | Human |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Clonality | Monoclonal |
| Isotype | scFv with Domain Crossover, Kappa;Lambda |
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Target | CD276, B7-H3, Costimulatory molecule, B7H3, 4Ig-B7-H3, B7 homolog 3, CD276 antigen, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain |
| Purification | Protein A/G purified from cell culture supernatant. |
| Endotoxin level | Please contact the lab for this information. |
| Expression system | Mammalian Cells |
| Accession | Q5ZPR3 & P07766 |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternative name | Bispecific, MGD009, RES281M1.1, hBRCA84D-hXR32-MP3M1.1, 2069959-72-2 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
Research Grade Obrindatamab
Overview
Description
Obrindatamab (HV612046) is a research-grade recombinant antibody targeting CD276. Produced in mammalian cells with native-like glycosylation.
Highlights
- ●Research Grade — For PK/PD studies, assay development, and ADA research.
- ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Images
 SDS-PAGE |
SDS-PAGE for Research Grade Obrindatamab |
 Bioactivity |
Detects CD276 in indirect ELISAs. |
 Bioactivity |
Detects CD3E in indirect ELISAs. |
 Bioactivity |
Detects CD276 in indirect ELISA. |
 Bioactivity |
Detects Recombinant Human CD276 Protein, C-His (Cat No.: HV612011) in indirect ELISA. |
 Western blot |
Western blot analysis was performed using anti-CD276 monoclonal antibody at 1ug/mL on various samples. Lane 1: recombinant human CD276 (Catalog No: HV612011) Lane 2: negative control |