| カタログ番号 | HC359046 |
| 宿主種 | Human |
| 種反応性 | Human |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS, pH 7.4. |
| 純度 | >95% purity as determined by SDS-PAGE. |
| クローン性 | Monoclonal |
| アイソタイプ | IgG4-Kappa |
| アプリケーション | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| ターゲット | Leukocyte surface antigen CD47, CD47, Antigenic surface determinant protein OA3, IAP, Integrin-associated protein, Protein MER6, MER6 |
| 精製 | Protein A/G purified from cell culture supernatant. |
| エンドトキシンレベル | Please contact the lab for this information. |
| 発現システム | Mammalian Cells |
| アクセッション番号 | Q08722 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternative name | CD47, IBI-188, 2283356-07-8 |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
Research Grade Letaplimab
概要
説明
Letaplimab (HC359046) is a research-grade recombinant antibody targeting CD47. Produced in mammalian cells with native-like glycosylation.
Highlights
- ●Research Grade — For PK/PD studies, assay development, and ADA research.
- ●Native Glycosylation — Mammalian expression ensures native-like patterns.
イメージ
 SDS-PAGE |
SDS-PAGE for Research Grade Letaplimab |
 Bioactivity |
Detects recombinant human CD47/MER6 (Catalog No: HC359011) in indirect ELISA |
 Flow cytometry |
Flow-cytometry using anti-human CD47 antibody. Hela cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD47 monoclonal antibody (Catalog HC359046, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer. |