| Catalog No. | HV974216 |
| Host species | Human |
| Species reactivity | Human |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Clonality | Monoclonal |
| Isotype | Ig(G1-kappa_G1-lambda2) |
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Target | B7-H1, Programmed cell death 1 ligand 1, PDCD1 ligand 1, PDCD1L1, B7 homolog 1, PDCD1LG1, PDL1, hPD-L1, Programmed death ligand 1, B7H1, PD-L1, CD274, Programmed cell death protein 1, Protein PD-1, hPD-1, PD1, PDCD1, CD279 |
| Purification | Protein A/G purified from cell culture supernatant. |
| Endotoxin level | Please contact the lab for this information. |
| Expression system | Mammalian Cells |
| Accession | Q9NZQ7 & Q15116 |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternative name | Bispecific, IBI318, IBI-318, IBI318, 2445259-99-2 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
Research Grade Reozalimab
Overview
Description
Reozalimab (HV974216) is a research-grade recombinant antibody targeting CD1. Produced in mammalian cells with native-like glycosylation.
Highlights
- ●Research Grade — For PK/PD studies, assay development, and ADA research.
- ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Images
 Bioactivity |
Detects PDL1 in indirect ELISA. |
 Bioactivity |
Detects recombinant human PD1 (Cat No.: HS870021) in indirect ELISA. |
 Flow CytoMetry |
Flow-cytometry using anti-human CD274 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human CD274 monoclonal antibody (Catalog: HV974216) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer. |
 Western blot |
Western blot analysis was performed using anti-CD274/PD-L1/B7-H1 monoclonal antibody at 1ug/mL on various samples. Lane 1: recombinant human CD274/PD-L1/B7-H1 (Catalog No: HV974011) Lane 2: negative control |