| Catalog No. | HF004206 |
| Host species | Humanized |
| Species reactivity | Human |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4. |
| Purity | >95% purity as determined by SDS-PAGE. |
| Clonality | Monoclonal |
| Isotype | IgG1-kappa-[scFv-heavy-lambda]2 |
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Target | HER1, Receptor tyrosine-protein kinase erbB-1, Proto-oncogene c-ErbB-1, Epidermal growth factor receptor, EGFR, ERBB1, ERBB, ERBB3, HER3, Proto-oncogene-like protein c-ErbB-3, Tyrosine kinase-type cell surface receptor HER3, Receptor tyrosine-protein kinase erbB-3 |
| Purification | Protein A/G purified from cell culture supernatant. |
| Endotoxin level | Please contact the lab for this information. |
| Expression system | Mammalian Cells |
| Accession | P00533 & P21860 |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternative name | Tetravalentbispecific, SI-1, SI-1X6.4, SI-B001, 2559704-24-2 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
Anti-Human EGFR/ERBB1 & ErbB3/Her3 Bispecific Reference Antibody (Izalontamab, RUO)
Overview
Images
 Bioactivity |
Detects EGFR in indirect ELISA. |
 Flow cytometry |
Flow-cytometry using anti-human ERBB3 antibody. HepG2 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human ERBB3 monoclonal antibody (Catalog HF004206, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer. |