| Catalog No. | HF004466 | ||||
| Host species | Human | ||||
| Tested applications | WB | ||||
| Species reactivity | Human | ||||
| Form | Liquid | ||||
| Storage buffer | 0.01M PBS, pH 7.4. | ||||
| Purity | >95% purity as determined by SDS-PAGE. | ||||
| Clonality | Monoclonal | ||||
| Isotype | immunoglobulin scFv-G1-scFv-scFv_L-kappa | ||||
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo, WB | ||||
| Target | HER1, Receptor tyrosine-protein kinase erbB-1, Proto-oncogene c-ErbB-1, Epidermal growth factor receptor, EGFR, ERBB1, ERBB, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain, B7-H1, Programmed cell death 1 ligand 1, PDCD1 ligand 1, PDCD1L1, B7 homolog 1, PDCD1LG1, PDL1, hPD-L1, Programmed death ligand 1, B7H1, PD-L1, CD274, Tumor necrosis factor receptor superfamily member 9, CD137, 4-1BB ligand receptor, CDw137, TNFRSF9, T-cell antigen ILA, T-cell antigen 4-1BB homolog, ILA | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Endotoxin level | Please contact the lab for this information. | ||||
| Expression system | Mammalian Cells | ||||
| Accession | P00533 & P07766 & Q9NZQ7 & Q07011 | ||||
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. | ||||
| Alternative name | 2599198-83-9 | ||||
| Product Usage Information |
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| Note | For research use only. Not suitable for clinical or therapeutic use. |
Anti-Human 4-1BB/TNFRSF9/CD137&CD3 epsilon&EGFR/EGFRvIII&PD-L1/B7-H1 Multispecific Reference Antibody (Umizortamig, RUO)
Overview
Images
 SDS-PAGE |
SDS-PAGE for Research Grade Umizortamig. |
 Bioactivity |
Detects recombinant CD137 (Catalog No: HC336011) in indirect ELISA. |
 Bioactivity |
Detects recombinant PDL1 (Catalog No: HV974011) in indirect ELISA. |
 Bioactivity |
Detects recombinant ERBB1 (Catalog No: HF004011) in indirect ELISA. |
 Western blot |
Western blot analysis was performed using anti-CD3E monoclonal antibody at 1ug/mL on various samples. Lane 1: recombinant human CD3E (Catalog No: HY057021) |