Research Grade Sotiburafusp Alfa

Catalog No.

HV974436

Host species

Humanized

Tested applications

WB

Species reactivity

Human

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Purity

>95% purity as determined by SDS-PAGE.

Clonality

Monoclonal

Isotype

IgG1-kappa, fused with humanized vascular endothelial growth factor receptor 1/VEGFR-1 extracellular domain fragment

Applications

ELISA, Bioactivity: FACS, Functional assay, Research in vivo, WB

Target

B7-H1, Programmed cell death 1 ligand 1, PDCD1 ligand 1, PDCD1L1, B7 homolog 1, PDCD1LG1, PDL1, hPD-L1, Programmed death ligand 1, B7H1, PD-L1, CD274, L-VEGF, N-VEGF, VEGF, VEGFA, VPF, Vascular endothelial growth factor A, long form, Vascular permeability factor

Purification

Protein A/G purified from cell culture supernatant.

Endotoxin level

Please contact the lab for this information.

Expression system

Mammalian Cells

Accession

Q9NZQ7 & P15692

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.

Alternative name

2637466-37-4

Product Usage Information

Application	Dilution
WB	1:500-1:2000

Note

For research use only. Not suitable for clinical or therapeutic use.

Sotiburafusp Alfa (HV974436) is a research-grade recombinant antibody targeting CD1. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

SDS-PAGE	SDS-PAGE for Research Grade Sotiburafusp Alfa.
Bioactivity	Detects recombinant PDL1 (Catalog No: HV974011) in indirect ELISA.
Western blot	Western blot analysis was performed using anti-PDL1 monoclonal antibody at 1ug/mL on various samples. Lane 1: recombinant human PDL1 (Catalog No: HV974011) Lane 2: Negative control