The PAC-1 antibody is derived from the fusion of SP-2 mouse myeloma cells with splenic lymphocytes from BALB/c mice that were immunized with human platelets. The PAC-1 recognizes an epitope on the glycoprotein IIb/IIIa (gpIIb/IIIa, αIIbβ3) complex of activated platelets at or near the platelet fibrinogen receptor.
Anti-Human PAC-1 Antibody (PAC-1)
Overview
Catalog No.
HY355407
Host species
Mouse
Species reactivity
Human
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Clonality
Monoclonal
Isotype
IgM, kappa
Applications
FCM
Target
CD41, ITGAB, GPIIb, ITGA2B, Platelet membrane glycoprotein IIb, GP2B, Integrin alpha-IIb, GPalpha IIb, GPIIIa, Integrin beta-3, CD61, ITGB3, Platelet membrane glycoprotein IIIa, GP3A, PAC-1
Endotoxin level
Please contact with the lab for this information.
Accession
P08514 & P05106
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
PAC-1
Note
For research use only.
Description
Images
Flow Cytometry
Flow-cytometry using anti-human PAC-1 antibody.Jurkat cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human PAC-1 antibody monoclonal antibody (Catalog # HY355407 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.
Flow Cytometry
Flow-cytometry using anti-human PAC-1 antibody.HepG2 cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human PAC-1 antibody monoclonal antibody (Catalog # HY355407 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.