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Research Grade Emactuzumab
Aperçu
Numéro de catalogue HY035026
Espèce hôte Humanized
Reactivité des espèces Human
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4.
Pureté >95% purity as determined by SDS-PAGE.
Clonalité Monoclonal
Isotype IgG1-kappa
Applications ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Cible CD115, CSF-1 receptor, CSF1R, M-CSF-R, CSF-1-R, Proto-oncogene c-Fms, Macrophage colony-stimulating factor 1 receptor, CSF-1R, FMS
Purification Protein A/G purified from cell culture supernatant.
Niveau d'endotoxines Please contact the lab for this information.
Système d'expression Mammalian Cells
Numéro d'accès P07333
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternative name RG7155, RO5509554, 1448221-67-7
Note For research use only. Not suitable for clinical or therapeutic use.
Description

Emactuzumab (HY035026) is a research-grade recombinant antibody targeting CD115. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.

Images


Bioactivity
Detects CD115/CSF1R in indirect ELISAs.

SDS-PAGE
SDS-PAGE for Research Grade Emactuzumab.

Flow CytoMetry
Flow-cytometry using PE anti-human CD115 antibody. THP-1 cells were stained with an irrelevant antibody (Blue Histogram) or an PE anti-human CD115 monoclonal antibody (Catalog: HY035026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.