Research Grade Istiratumab
Overview
| Catalog No. |
HY353076 |
| Host species |
Human |
| Species reactivity |
Human |
| Form |
Liquid |
| Storage buffer |
0.01M PBS, pH 7.4. |
| Purity |
>95% purity as determined by SDS-PAGE. |
| Clonality |
Monoclonal |
| Isotype |
IgG1-kappa-[scFv]2 |
| Applications |
ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Target |
CD221, Insulin-like growth factor 1 receptor, IGF1R, Insulin-like growth factor I receptor, IGF-I receptor, ERBB3, HER3, Proto-oncogene-like protein c-ErbB-3, Tyrosine kinase-type cell surface receptor HER3, Receptor tyrosine-protein kinase erbB-3 |
| Purification |
Protein A/G purified from cell culture supernatant. |
| Endotoxin level |
Please contact the lab for this information. |
| Expression system |
Mammalian Cells |
| Accession |
P08069 & P21860 |
| Stability and Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Alternative name |
Bispecific, MM-005, MM-141, 1509928-04-4 |
| Note |
For research use only. Not suitable for clinical or therapeutic use. |
Images
 SDS-PAGE |
SDS-PAGE for Research Grade Istiratumab. |
 Flow CytoMetry |
Flow-cytometry using anti-human ERBB3 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human ERBB3 monoclonal antibody (Catalog: HY353076) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer. |