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InVivoMAb Anti-Human Coagulation Factor XII Antibody (Iv0164) (HF664010)

InVivoMAb Anti-Human Coagulation Factor XII Antibody (Iv0164)
InVivoMAb Anti-Human Coagulation Factor XII Antibody (Iv0164)
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  • 100ug
  • 1mg
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Overview
Catalog No.HF664010
Description
InVivoMAb Anti-Human F12 Antibody (Iv0164) [Iv0164] (HF664010) is a human monoclonal antibody detecting F12 in ELISA, Neutralization, WB. Suitable for Human.
Highlights
  • Multi-Application — Validated across multiple applications.
Species reactivityHuman
ApplicationsELISA, Neutralization, WB
Host speciesHuman
IsotypeIgG4, lambda
Clone IDIv0164
Clonality Monoclonal
Target F12, HAF, Hageman factor, Beta-factor XIIa part 2, Coagulation factor XII
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Associated products pH 7.4 Dilution Buffer
Purification Protein A/G purified from cell culture supernatant.
Accession P00748
Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Coagulation factor XII (F12/Coagulationfactor XII) is a ~67 kDa protein. Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa.

1. Naito, K. et al. (1991) The Journal of biological chemistry 266, 7353-8. PMID: 2019570
2. MacQuarrie, JL. et al. (2011) Blood 117, 4134-41. PMID: 21304106
3. Brunnée, T. et al. (1993) Blood 81, 580-6. PMID: 8427954
Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • InVivoMAb Anti-Human Coagulation Factor XII Antibody (Iv0164)

    SDS-PAGE

    SDS-PAGE for InVivoMAb Anti-Human F12 Antibody (Iv0164).

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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