Anti-PTK2 Polyclonal Antibody (HC379014)

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Precio(USD): $

Especificación:

50ug
100ug

Número:

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Imágenes
Referencias
Datasheet

Vista general

Número de catálogo

HC379014

Descripción

Anti-PTK2 Polyclonal Antibody (HC379014) is a rabbit polyclonal antibody detecting PTK2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Chicken, and Xenopus laevis.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactividad de especies

Human, Mouse, Rat, Chicken, Xenopus laevis

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Isotipo

IgG

Clonalidad

Polyclonal

Inmunógeno

E. coli - derived recombinant Human PTK2 (Gly798-Ala1041).

Objetivo

p125FAK, pp125FAK, PPP1R71, Protein-tyrosine kinase 2, FADK 1, FAK1, Focal adhesion kinase 1, FAK, PTK2, Focal adhesion kinase-related nonkinase, FRNK, Protein phosphatase 1 regulatory subunit 71

Purificación

Purified by antigen affinity column.

Número de acceso

Q05397

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Focal adhesion kinase 1 (PTK2) is a ~119 kDa protein. Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development and placenta development. Required for embryonic angiogenesis, normal cardiomyocyte migration and proliferation, and normal heart development. Regulates axon growth and neuronal cell migration, axon branching and synapse formation; required for normal development of the nervous system. Plays a role in osteogenesis and differentiation of osteoblasts.

1. Tachibana, K. et al. (1997) The Journal of biological chemistry 272, 29083-90. PMID: 9360983

Nota

For research use only.

Imágenes

Western blot

Western blot analysis was performed using anti-PTK2 polyclonal antibody at 1ug/mL on recombinant PTK2 (Catalog No. HC379012).

Referencias

Datasheet

Anti-PTK2 Polyclonal Antibody.pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo