Anti-HRSV-A G/Major surface glycoprotein G Antibody (3D3) (VK562023)

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Numéro de catalogue

VK562023

Description

Anti-HRSV-A G/Major surface glycoprotein G Antibody (3D3) [3D3] (VK562023) is a human monoclonal antibody detecting Major surface glycoprotein G in ELISA, WB.

Reactivité des espèces

Human respiratory syncytial virus A (strain A2)

Applications

ELISA, WB

Espèce hôte

Human

Isotype

IgG1, kappa

ID de clone

3D3

Clonalité

Monoclonal

Cible

G, Major surface glycoprotein G, Attachment glycoprotein G, Membrane-bound glycoprotein, mG, RSV

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

P03423

RRID

Anti-HRSV-A G/Major surface glycoprotein G Antibody (3D3) (abinScience Cat# VK562023, RRID:AB_3725264)

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Major surface glycoprotein G is a ~32 kDa protein. Attaches the virion to the host cell membrane by interacting with heparan sulfate, initiating the infection. Interacts with host CX3CR1, the receptor for the CX3C chemokine fractalkine, to modulate the immune response and facilitate infection. Unlike the other paramyxovirus attachment proteins, lacks both neuraminidase and hemagglutinating activities (Probable).

1. Feldman, SA. et al. (1999) Journal of virology 73, 6610-7. PMID: 10400758

2. Feldman, SA. et al. (2000) Journal of virology 74, 6442-7. PMID: 10864656

3. Levine, S. et al. (1987) The Journal of general virology 68 ( Pt 9), 2521-4. PMID: 3655746

4. Tripp, RA. et al. (2001) Nature immunology 2, 732-8. PMID: 11477410

5. Jeong, KI. et al. (2015) PloS one 10, e0130517. PMID: 26107373

6. Johnson, SM. et al. (2015) PLoS pathogens 11, e1005318. PMID: 26658574

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-HRSV-A G/Major surface glycoprotein G Antibody (3D3).

Reférences

Fiche technique

Anti-HRSV-A G/Major surface glycoprotein G Antibody (3D3).pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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