Anti-Nipah virus/NiV Fusion glycoprotein F2 Antibody (11F10) (VK521023)

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50ug
100ug
1mg

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Datasheet

Vista general

Número de catálogo

VK521023

Descripción

Anti-Nipah virus/NiV Fusion glycoprotein F2 Antibody (11F10) [11F10] (VK521023) is a human monoclonal antibody detecting Fusion glycoprotein F2 in IP, WB. Suitable for Nipah virus (NiV).

Reactividad de especies

Nipah virus (NiV)

Aplicaciones

IP, WB

Especie huésped

Human

Isotipo

IgG1

ID de clon

11F10

Clonalidad

Monoclonal

Objetivo

Fusion glycoprotein, Protein F, Fusion glycoprotein F2

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

Q9IH63

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Fusion glycoprotein F0 (Fusion glycoprotein F2) is a ~60 kDa protein. Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm.

Nota

For research use only.

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