Anti-Human CD340/ERBB2/HER2 Antibody (FRP5) (HY286063)

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50ug
100ug
1mg

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Aperçu

Numéro de catalogue

HY286063

Description

Anti-Human CD340/ERBB2/HER2 Antibody (FRP5) [FRP5] (HY286063) is a mouse monoclonal antibody detecting CD340 in ELISA, IF, WB. Suitable for Human.

Highlights

●Multi-Application — Validated across multiple applications.

Reactivité des espèces

Human

Applications

ELISA, IF, WB

Espèce hôte

Mouse

Isotype

IgG2a, kappa

ID de clone

FRP5

Clonalité

Monoclonal

Cible

Receptor tyrosine-protein kinase erbB-2, 2.7.10.1, Metastatic lymph node gene 19 protein, MLN 19, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Tyrosine kinase-type cell surface receptor HER2, p185erbB2, CD340, ERBB2, HER2, MLN19, NEU, NGL

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

P04626

RRID

Anti-Human CD340/ERBB2/HER2 Antibody (FRP5) (abinScience Cat# HY286063, RRID:AB_3729458)

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Receptor tyrosine-protein kinase erbB-2 (CD340/ERBB2) is a ~137 kDa protein. Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. CD340 is the therapeutic target of trastuzumab (Herceptin) and trastuzumab deruxtecan (Enhertu).

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human CD340/ERBB2/HER2 Antibody (FRP5)

Reférences

Fiche technique

Anti-Human CD340/ERBB2/HER2 Antibody (FRP5).pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

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