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Anti-Siltuximab Neutralizing Antibody (1A455) (HY328035)

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Anti-Siltuximab Neutralizing Antibody (1A455)

Anti-Siltuximab Neutralizing Antibody (1A455)

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Aperçu

Numéro de catalogue	HY328035
Description	Anti-Siltuximab Neutralizing Antibody (1A455) [1A455] (HY328035) is a mouse monoclonal antibody in ELISA.
Applications	ELISA
Espèce hôte	Mouse
Isotype	IgG1
ID de clone	1A455
Clonalité	Monoclonal
Immunogène	E. coli - derived recombinant protein.
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P05231
RRID	Anti-Siltuximab Neutralizing Antibody (1A455) (abinScience Cat# HY328035, RRID:AB_3730105)
Forme	Liquid
Tampon de stockage	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte	Interleukin-6 is a ~23 kDa protein. Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable).
Note	For research use only.

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SDS-PAGE

SDS-PAGE for Anti-Siltuximab Neutralizing Antibody (1A455)

Reférences

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Anti-Siltuximab Neutralizing Antibody (1A455).pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

=

Concentration

×

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

×

V₁ (Stock Vol.)

=

Working Solution

C₂ (Working Conc.)

×

V₂ (Working Vol.)

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Anti-Siltuximab Neutralizing Antibody (1A455)