

| Número de catálogo | GY328014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Chicken IL6 Polyclonal Antibody (GY328014) is a rabbit polyclonal antibody detecting IL6 in WB, IHC, ELISA. Suitable for Chicken.
Highlights
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| Reactividad de especies | Chicken | ||||||||
| Aplicaciones | WB, IHC, ELISA | ||||||||
| Especie huésped | Rabbit | ||||||||
| Isotipo | IgG | ||||||||
| Especies | Gallus gallus (Chicken) | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Inmunógeno | E. coli - derived recombinant Chicken IL6 (Val47-Ala241). | ||||||||
| Objetivo | IL6 | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Pureza | >90% as determined by SDS-PAGE. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q90YI0 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Nombres alternativos | Interleukin-6, ChIL-6, IL-6, IL6 | ||||||||
| Fondo | Interleukin-6 (IL6) is a ~26 kDa protein. Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway. The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells. IL6 is the therapeutic target of tocilizumab (Actemra). | ||||||||
| Nota | For research use only. |
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