

| Numéro de catalogue | HY286166 | ||||
|---|---|---|---|---|---|
| Description |
Research Grade dulpatatug (HY286166) is a human monoclonal antibody. Suitable for Human.
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| Reactivité des espèces | Human | ||||
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo | ||||
| Espèce hôte | Human | ||||
| Isotype | IgG1, kappa | ||||
| Clonalité | Monoclonal | ||||
| Niveau d'endotoxines | < 10 EU/mg | ||||
| Pureté | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Numéro d'accès | P04626 | ||||
| Forme | Liquid | ||||
| Tampon de stockage | 0.01 M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -89°C long term. | ||||
| Contexte | Receptor tyrosine-protein kinase erbB-2 (CD340/ERBB2) is a ~137 kDa protein. Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. | ||||
| Note | For research use only. |
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