Anti-CD20/MS4A1 Polyclonal Antibody (HY257014)

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Precio(USD): $

Especificación:

50ug
100ug

Número:

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Datasheet

Vista general

Número de catálogo

HY257014

Descripción

Anti-CD20/MS4A1 Polyclonal Antibody (HY257014) is a rabbit polyclonal antibody detecting MS4A1 in ELISA, IHC, WB, IF. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactividad de especies

Human

Aplicaciones

ELISA, IHC, WB, IF

Especie huésped

Rabbit

Isotipo

IgG

Clonalidad

Polyclonal

Inmunógeno

E. coli - derived recombinant Human CD20/MS4A1 (Ile143-Ser188).

Objetivo

B-lymphocyte surface antigen B1, Membrane-spanning 4-domains subfamily A member 1, MS4A1, Leukocyte surface antigen Leu-16, B-lymphocyte antigen CD20, Bp35, CD20

Nivel de endotoxinas

Please contact with the lab for this information.

Purificación

Purified by antigen affinity column.

Número de acceso

P11836

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

B-lymphocyte antigen CD20 (MS4A1) is a ~33 kDa protein. B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR. CD20 is the therapeutic target of rituximab (MabThera) and obinutuzumab (Gazyva).

1. Li, H. et al. (2003) The Journal of biological chemistry 278, 42427-34. PMID: 12920111

2. Tedder, TF. et al. (1985) Journal of immunology (Baltimore, Md. : 1950) 135, 973-9. PMID: 3925015

3. Bubien, JK. et al. (1993) The Journal of cell biology 121, 1121-32. PMID: 7684739

4. Polyak, MJ. et al. (2008) The Journal of biological chemistry 283, 18545-52. PMID: 18474602

Nota

For research use only.

Imágenes

Western blot

Western blot analysis was performed using anti-CD20/MS4A1 polyclonal antibody at 1ug/mL on recombinant CD20/MS4A1 (Catalog No. HY257022).

Referencias

Datasheet