Anti-Human CD40/TNFRSF5 Antibody (SAA1387) (HB782307)

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Número de catálogo	HB782307
Descripción	Anti-Human CD40/TNFRSF5 Antibody (SAA1387) [SAA1387] (HB782307) is a mouse monoclonal antibody detecting TNFRSF5 in FCM. Suitable for Human. Highlights ●Flow Cytometry — Validated for flow cytometry applications.
Reactividad de especies	Human
Aplicaciones	FCM
Especie huésped	Mouse
Isotipo	IgG1, kappa
ID de clon	SAA1387
Clonalidad	Monoclonal
Objetivo	Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor, TNFRSF5, CDw40, CD40
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P25942
Forma	Liquid
Buffer de almacenamiento	0.01M PBS, pH 7.4, 0.09% Sodium azide. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo	Tumor necrosis factor receptor superfamily member 5 (CD40/TNFRSF5) is a ~30 kDa protein. Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. 1. Takada, YK. et al. (2019) Journal of immunology (Baltimore, Md. : 1950) 203, 1383-1391. PMID: 31331973
Nota	For research use only.

Imágenes

Bioactivity

Detects CD40/TNFRSF5 in indirect ELISAs.
Flow Cytometry

Flow-cytometry using anti-human CD40 antibody.Daudi cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD40 antibody monoclonal antibody (Catalog # HB782307 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.