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Anti-Human CD183/CXCR3 Antibody (5H7) (HW606207)

Anti-Human CD183/CXCR3 Antibody (5H7)
Anti-Human CD183/CXCR3 Antibody (5H7)
Prix(USD) : $
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  • 100ug
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Aperçu
Numéro de catalogueHW606207
Description
Anti-Human CD183/CXCR3 Antibody (5H7) [5H7] (HW606207) is a mouse monoclonal antibody detecting CXCR3 in FCM. Suitable for Human.
Highlights
  • Flow Cytometry — Validated for flow cytometry applications.
Reactivité des espècesHuman
ApplicationsFCM
Espèce hôteMouse
IsotypeIgG2a, kappa
ID de clone5H7
Clonalité Monoclonal
Cible CXCR3, G protein-coupled receptor 9, CXC-R3, Interferon-inducible protein 10 receptor, IP-10 receptor, C-X-C chemokine receptor type 3, GPR9, CD183, CKR-L2, CXCR-3
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P49682
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte

C-X-C chemokine receptor type 3 (CD183/CXCR3) is a ~40 kDa protein. Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of human mesangial cells (HMC) through a heterotrimeric G-protein signaling pathway. Binds to CCL21. Probably promotes cell chemotaxis response. Upon activation by PF4, induces activated T-lymphocytes migration mediated via downstream Ras/extracellular signal-regulated kinase (ERK) signaling.

1. Lasagni, L. et al. (2003) The Journal of experimental medicine 197, 1537-49. PMID: 12782716
Note For research use only.
Images
  • Anti-Human CD183/CXCR3 Antibody (5H7)

    SDS-PAGE

    SDS-PAGE for Anti-Human CD183/CXCR3 Antibody (5H7)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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