

| Numéro de catalogue | HW606207 |
|---|---|
| Description |
Anti-Human CD183/CXCR3 Antibody (5H7) [5H7] (HW606207) is a mouse monoclonal antibody detecting CXCR3 in FCM. Suitable for Human.
Highlights
|
| Reactivité des espèces | Human |
| Applications | FCM |
| Espèce hôte | Mouse |
| Isotype | IgG2a, kappa |
| ID de clone | 5H7 |
| Clonalité | Monoclonal |
| Cible | CXCR3, G protein-coupled receptor 9, CXC-R3, Interferon-inducible protein 10 receptor, IP-10 receptor, C-X-C chemokine receptor type 3, GPR9, CD183, CKR-L2, CXCR-3 |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Numéro d'accès | P49682 |
| Forme | Liquid |
| Tampon de stockage | 0.01M PBS, pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Contexte | C-X-C chemokine receptor type 3 (CD183/CXCR3) is a ~40 kDa protein. Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of human mesangial cells (HMC) through a heterotrimeric G-protein signaling pathway. Binds to CCL21. Probably promotes cell chemotaxis response. Upon activation by PF4, induces activated T-lymphocytes migration mediated via downstream Ras/extracellular signal-regulated kinase (ERK) signaling. 1. Lasagni, L. et al. (2003) The Journal of experimental medicine 197, 1537-49. PMID: 12782716 |
| Note | For research use only. |

SDS-PAGE for Anti-Human CD183/CXCR3 Antibody (5H7)




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