Anti-Rat VEGFA Antibody (SAA0447), APC (RB941237)

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Numéro de catalogue	RB941237
Description	Anti-Rat VEGFA Antibody (SAA0447), APC [SAA0447] (RB941237) is a mouse monoclonal antibody detecting VEGFA in ELISA, FCM. Suitable for Rat. Highlights ●Flow Cytometry — Validated for flow cytometry applications. ●Fluorescent Label — Direct conjugate for streamlined workflows.
Reactivité des espèces	Rat
Applications	ELISA, FCM
Espèce hôte	Mouse
Isotype	IgG2a, kappa
ID de clone	SAA0447
Conjugaison	APC
Clonalité	Monoclonal
Cible	Vascular endothelial growth factor A, VPF, VEGFA, VEGF, Vascular permeability factor, VEGF-A
Niveau d'endotoxines	Please contact with the lab for this information.
Numéro d'accès	P16612
Forme	Liquid
Tampon de stockage	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Contexte	Vascular endothelial growth factor A (VEGFA) is a ~25 kDa protein. Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. May play a role in increasing vascular permeability during lactation, when increased transport of molecules from the blood is required for efficient milk protein synthesis. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development. VEGFA is the therapeutic target of bevacizumab (Avastin).
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Rat VEGFA Antibody (SAA0447), APC.pdf

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