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Anti-Human Reticulon-4/RTN4 Antibody (SAA0170), APC (HP021137)

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Aperçu
Numéro de catalogueHP021137
Description
Anti-Human Reticulon-4/RTN4 Antibody (SAA0170), APC [SAA0170] (HP021137) is a human monoclonal antibody detecting Reticulon-4 in ELISA, FCM. Suitable for Human.
Highlights
  • Flow Cytometry — Validated for flow cytometry applications.
  • Fluorescent Label — Direct conjugate for streamlined workflows.
Reactivité des espècesHuman
ApplicationsELISA, FCM
Espèce hôteHuman
IsotypeIgG1
ID de cloneSAA0170
ConjugaisonAPC
Clonalité Monoclonal
Cible RTN-x, Reticulon-4, Neuroendocrine-specific protein, Neuroendocrine-specific protein C homolog, NOGO, Nogo protein, Neurite outgrowth inhibitor, NSP, Reticulon-5, KIAA0886, RTN4, Foocen
Niveau d'endotoxines Please contact with the lab for this information.
Numéro d'accès Q9NQC3
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Store at 4°C for 12 months. Protect from light. Do not freeze.
Contexte

Reticulon-4 (RTN4) is a ~129 kDa protein. Required to induce the formation and stabilization of endoplasmic reticulum (ER) tubules. They regulate membrane morphogenesis in the ER by promoting tubular ER production. They influence nuclear envelope expansion, nuclear pore complex formation and proper localization of inner nuclear membrane proteins. However each isoform have specific functions mainly depending on their tissue expression specificities (Probable).

1. Yamamoto, Y. et al. (2014) The Biochemical journal 458, 69-79. PMID: 24262037
2. Urade, T. et al. (2014) The Kobe journal of medical sciences 60, E57-65. PMID: 25612671
3. Wang, S. et al. (2016) eLife 5. PMID: 27619977
4. Rämö, O. et al. (2016) Scientific reports 6, 35969. PMID: 27786289
5. Christodoulou, A. et al. (2016) Journal of cell science 129, 1552-65. PMID: 26906412
Note For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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