

| Numéro de catalogue | HP021137 |
|---|---|
| Description |
Anti-Human Reticulon-4/RTN4 Antibody (SAA0170), APC [SAA0170] (HP021137) is a human monoclonal antibody detecting Reticulon-4 in ELISA, FCM. Suitable for Human.
Highlights
|
| Reactivité des espèces | Human |
| Applications | ELISA, FCM |
| Espèce hôte | Human |
| Isotype | IgG1 |
| ID de clone | SAA0170 |
| Conjugaison | APC |
| Clonalité | Monoclonal |
| Cible | RTN-x, Reticulon-4, Neuroendocrine-specific protein, Neuroendocrine-specific protein C homolog, NOGO, Nogo protein, Neurite outgrowth inhibitor, NSP, Reticulon-5, KIAA0886, RTN4, Foocen |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Numéro d'accès | Q9NQC3 |
| Forme | Liquid |
| Tampon de stockage | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Stabilité et stockage | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Contexte | Reticulon-4 (RTN4) is a ~129 kDa protein. Required to induce the formation and stabilization of endoplasmic reticulum (ER) tubules. They regulate membrane morphogenesis in the ER by promoting tubular ER production. They influence nuclear envelope expansion, nuclear pore complex formation and proper localization of inner nuclear membrane proteins. However each isoform have specific functions mainly depending on their tissue expression specificities (Probable). 1. Yamamoto, Y. et al. (2014) The Biochemical journal 458, 69-79. PMID: 24262037 2. Urade, T. et al. (2014) The Kobe journal of medical sciences 60, E57-65. PMID: 25612671 3. Wang, S. et al. (2016) eLife 5. PMID: 27619977 4. Rämö, O. et al. (2016) Scientific reports 6, 35969. PMID: 27786289 5. Christodoulou, A. et al. (2016) Journal of cell science 129, 1552-65. PMID: 26906412 |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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