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Anti-Human CD140b/PDGFRB Antibody (SAA0058), PE (HY260127)

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Anti-Human CD140b/PDGFRB Antibody (SAA0058), PE

Anti-Human CD140b/PDGFRB Antibody (SAA0058), PE

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Datasheet

Vista general

Número de catálogo	HY260127
Descripción	Anti-Human CD140b/PDGFRB Antibody (SAA0058), PE [SAA0058] (HY260127) is a human monoclonal antibody detecting CD140b in FCM. Suitable for Human. Highlights ●Flow Cytometry — Validated for flow cytometry applications.
Reactividad de especies	Human
Aplicaciones	FCM
Especie huésped	Human
Isotipo	IgG4, kappa
ID de clon	SAA0058
Conjugación	PE
Clonalidad	Monoclonal
Objetivo	Beta-type platelet-derived growth factor receptor, Beta platelet-derived growth factor receptor, CD140b, Platelet-derived growth factor receptor 1, PDGFRB, PDGF-R-beta, Platelet-derived growth factor receptor beta, CD140 antigen-like family member B, PDGFR-1, PDGFR1, PDGFR-beta, PDGFR
Nivel de endotoxinas	Please contact with the lab for this information.
Número de acceso	P09619
Forma	Liquid
Buffer de almacenamiento	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Store at 4°C for 12 months. Protect from light. Do not freeze.
Fondo	Platelet-derived growth factor receptor beta (CD140b/PDGFRB) is a ~123 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. Plays a role in the migration of vascular smooth muscle cells and the formation of neointima at vascular injury sites. Required for normal development of the cardiovascular system. Required for normal recruitment of pericytes (mesangial cells) in the kidney glomerulus, and for normal formation of a branched network of capillaries in kidney glomeruli.
Nota	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

Imágenes

Flow CytoMetry

Flow-cytometry using PE anti-human CD140b antibody. MG-63 cells were fixed and permeabilized, then stained with an irrelevant antibody (Blue Histogram) or an PE anti-human CD140b monoclonal antibody (Catalog: HY260127, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

Referencias

Datasheet

Anti-Human CD140b/PDGFRB Antibody (SAA0058), PE.pdf

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Anti-Human CD140b/PDGFRB Antibody (SAA0058), PE