

| Numéro de catalogue | VK632013 | ||||
|---|---|---|---|---|---|
| Description |
Anti-RABV G/Glycoprotein Antibody (523-11#) [523-11#] (VK632013) is a mouse monoclonal antibody detecting Glycoprotein G in ELISA, Neutralization. Suitable for Rabies lyssavirus.
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| Reactivité des espèces | Rabies lyssavirus, Rabies virus (strain HEP-Flury) (RABV), Rabies virus (strain CVS-11) (RABV) | ||||
| Applications | ELISA, Neutralization | ||||
| Espèce hôte | Mouse | ||||
| Isotype | IgG1, kappa | ||||
| ID de clone | 523-11# | ||||
| Clonalité | Monoclonal | ||||
| Cible | G, Glycoprotein G | ||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||
| Pureté | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Numéro d'accès | Q0GBY1, O92284, P15199, P19462 | ||||
| RRID | Anti-RABV G/Glycoprotein Antibody (523-11#) (abinScience Cat# VK632013, RRID:AB_3725360) |
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| Forme | Liquid | ||||
| Tampon de stockage | 0.01M PBS, pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Contexte | Glycoprotein is a ~58 kDa protein. Attaches the virus to host cellular receptor, inducing endocytosis of the virion by using different host proteins including TFRC, GRM2 and ITGB1. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells. | ||||
| Note | For research use only. |

SDS-PAGE for Anti-RABV G/Glycoprotein Antibody (523-11#).
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