InVivoMAb Anti-Human CD40/TNFRSF5 Antibody (Iv0136) (HB782010)

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100ug
1mg

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Aperçu

Numéro de catalogue	HB782010
Description	InVivoMAb Anti-Human CD40/TNFRSF5 Antibody (Iv0136) [Iv0136] (HB782010) is a human monoclonal antibody detecting Tumor necrosis factor receptor superfamily member 5 in ELISA, Neutralization. Suitable for Human.
Reactivité des espèces	Human
Applications	ELISA, Neutralization
Espèce hôte	Human
Isotype	IgG1, kappa
ID de clone	Iv0136
Clonalité	Monoclonal
Cible	Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor, TNFRSF5, CDw40, CD40
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P25942
RRID	InVivoMAb Anti-Human CD40/TNFRSF5 Antibody (Iv0136) (abinScience Cat# HB782010, RRID:AB_3726920)
Forme	Liquid
Tampon de stockage	0.01M PBS, pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte	Tumor necrosis factor receptor superfamily member 5 (CD40/TNFRSF5) is a ~30 kDa protein. Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. 1. Takada, YK. et al. (2019) Journal of immunology (Baltimore, Md. : 1950) 203, 1383-1391. PMID: 31331973
Note	For research use only. Not suitable for clinical or therapeutic use.

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Bioactivity

Detects CD40/TNFRSF5 in indirect ELISAs.
SDS-PAGE

SDS-PAGE for InVivoMAb Anti-Human CD40/TNFRSF5 Antibody (Iv0136).
Flow CytoMetry

Flow-cytometry using APC anti-human CD40 antibody. U2OS cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human CD40 monoclonal antibody (Catalog: HB782010, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.
Flow CytoMetry

Flow-cytometry using FITC anti-human CD40 antibody. U2OS cells were stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human CD40 monoclonal antibody (Catalog: HB782010, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.