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Research Grade Ecromeximab (YP464016)

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Research Grade Ecromeximab

Research Grade Ecromeximab

Research Grade Ecromeximab

Research Grade Ecromeximab

Prix(USD) : $

Spécification :

100ug
1mg

Nombre :

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Aperçu
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Aperçu

Numéro de catalogue	YP464016
Description	Ecromeximab (YP464016) is a research-grade recombinant antibody targeting Ganglioside GD3. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espèces	General
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Chimeric
Isotype	IgG1-kappa
Système d'expression	Mammalian Cells
Clonalité	Monoclonal
Cible	Ganglioside GD3
Niveau d'endotoxines	Please contact the lab for this information.
Pureté	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	PubChem CID: 20057323
Forme	Liquid
Tampon de stockage	0.01M PBS, pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Noms alternatifs	KM871, KW-2871, CAS: 292819-64-8
Contexte	Mitumomab is an anti-idiotypic mouse IgG2b monoclonal antibody that mimics the ganglioside GD3. Mitumomab can be used for the research of small-cell lung carcinoma. • GD3 ganglioside and apoptosis., PMID:12531552 • Ganglioside GD3: structure, cellular distribution, and possible function., PMID:3903474 • Ganglioside GD3 as a raft component in cell death regulation., PMID:21554197 • A reappraisal of ganglioside GD3 expression in the CNS., PMID:8721669 • Ganglioside GD3 regulates neural stem cell quiescence and controls postnatal neurogenesis., PMID:37667994 • Ganglioside GD3 is up-regulated in microglia and regulates phagocytosis following global cerebral ischemia., PMID:34133773 • Ganglioside GD3 regulates dendritic growth in newborn neurons in adult mouse hippocampus via modulation of mitochondrial dynamics., PMID:32743804 • Possible regulation of ganglioside GD3 synthase gene expression with DNA methylation in human glioma cells., PMID:36897478 • Ganglioside GD3 Regulates Inflammation and Epithelial-to-Mesenchymal Transition in Human Nasal Epithelial Cells., PMID:38612859 • Development of Fluorescent Ganglioside GD3 and GQ1b Analogs for Elucidation of Raft-Associated Interactions., PMID:32951428
Note	For research use only. Not suitable for clinical or therapeutic use.

Images

Bioactivity

SEC-HPLC detection for Research Grade Ecromeximab.
SDS-PAGE

SDS-PAGE for Research Grade Ecromeximab.

Reférences

Fiche technique

Research Grade Ecromeximab.pdf

Formula

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Research Grade Ecromeximab