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Research Grade Regavirumab (VK665016)

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Research Grade Regavirumab

Research Grade Regavirumab

Research Grade Regavirumab

Research Grade Regavirumab

Prix(USD) : $

Spécification :

100ug
1mg

Nombre :

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Aperçu
Images
Reférences
Fiche technique

Aperçu

Numéro de catalogue	VK665016
Description	Regavirumab (VK665016) is a research-grade recombinant antibody targeting Envelope glycoprotein B. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espèces	Human cytomegalovirus (HCMV/HHV-5)
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Isotype	IgG1, kappa
Système d'expression	Mammalian Cells
Clonalité	Monoclonal
Cible	Envelope glycoprotein B, gB, UL55
Niveau d'endotoxines	Please contact the lab for this information.
Pureté	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P06473
Forme	Liquid
Tampon de stockage	0.01M PBS, pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Noms alternatifs	C23, MCAC23, TI-23, 153101-26-9
Contexte	Envelope glycoprotein B (gB) is a ~102 kDa protein. Envelope glycoprotein that plays a role in host cell entry, cell to-cell virus transmission, and fusion of infected cells. May be involved in the initial attachment via binding to heparan sulfate together with the gM/gN complex that binds heparin with higher affinity. Interacts with host integrin ITGB1, PDGFRA and EGFR that likely serve as postattachment entry receptors. Also participates in the fusion of viral and cellular membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.
Note	For research use only. Not suitable for clinical or therapeutic use.

Images

Bioactivity

SEC-HPLC detection for Research Grade Regavirumab.
SDS-PAGE

SDS-PAGE for Research Grade Regavirumab.

Reférences

Fiche technique

Research Grade Regavirumab.pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

=

Concentration

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Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

×

V₁ (Stock Vol.)

=

Working Solution

C₂ (Working Conc.)

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V₂ (Working Vol.)

Recommandation

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Research Grade Regavirumab