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Research Grade cT84.66 (HY546056)

Research Grade cT84.66
Research Grade cT84.66
Research Grade cT84.66
Research Grade cT84.66
Research Grade cT84.66
Research Grade cT84.66
Precio(USD): $
Especificación:
  • 100ug
  • 1mg
Número:
Contáctenos
  • Vista general

  • Imágenes

  • Referencias

  • Datasheet

Vista general
Número de catálogoHY546056
Descripción
cT84.66 (HY546056) is a research-grade recombinant antibody targeting CD66. Produced in mammalian cells with native-like glycosylation.
Highlights
  • Research Grade — For PK/PD studies, assay development, and ADA research.
  • Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especiesHuman
AplicacionesELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huéspedChimeric
IsotipoIgG1
Sistema de expresión Mammalian Cells
Clonalidad Monoclonal
Objetivo Meconium antigen 100, CEACAM5, CEA, CD66e, Carcinoembryonic antigen-related cell adhesion molecule 5, Carcinoembryonic antigen
Nivel de endotoxinas Please contact the lab for this information.
Pureza >95% purity as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso P06731
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Nombres alternativos90Y-cT84.66, T84.66
Fondo

Cell adhesion molecule CEACAM5 (CD66e) is a ~76 kDa protein. Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells.

1. Taheri, M. et al. (2000) The Journal of biological chemistry 275, 26935-43. PMID: 10864933
2. Ordoñez, C. et al. (2000) Cancer research 60, 3419-24. PMID: 10910050
3. Oikawa, S. et al. (1989) Biochemical and biophysical research communications 164, 39-45. PMID: 2803308
Nota For research use only. Not suitable for clinical or therapeutic use.
Imágenes
  • Research Grade cT84.66

    Bioactivity

    Detects Human CD66e/CEA/CEACAM5 in indirect ELISAs.

  • Research Grade cT84.66

    SDS-PAGE

    SDS-PAGE for Research Grade cT84.66.

  • Research Grade cT84.66

    Western blot

    Western blot analysis was performed using anti-CD66e/CEA/CEACAM5 monoclonal antibody at 1ug/mL on various samples.
    Lane 1: recombinant human CD66e/CEA/CEACAM5 (Catalog No: HY546011)
    Lane 2: negative control

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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