Research Grade Ranibizumab (HB941016)

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Precio(USD): $

Especificación:

100ug
1mg

Número:

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Vista general
Imágenes
Referencias
Datasheet

Vista general

Número de catálogo	HB941016
Descripción	Ranibizumab (HB941016) is a research-grade recombinant antibody targeting Vascular endothelial growth factor A. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huésped	Humanized
Isotipo	Fab-G1-kappa
Sistema de expresión	Mammalian Cells
Clonalidad	Monoclonal
Objetivo	Vascular endothelial growth factor A, VPF, VEGFA, VEGF, Vascular permeability factor, VEGF-A
Nivel de endotoxinas	Please contact the lab for this information.
Pureza	>95% purity as determined by SDS-PAGE.
Purificación	Protein L purified from cell culture supernatant.
Número de acceso	P15692
Forma	Liquid
Buffer de almacenamiento	0.01M PBS, pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Nombres alternativos	Fab-12variantY0317, RhuFab, 347396-82-1
Fondo	Vascular endothelial growth factor A, long form (VEGFA) is a ~43 kDa protein. Participates in the induction of key genes involved in the response to hypoxia and in the induction of angiogenesis such as HIF1A. Involved in protecting cells from hypoxia-mediated cell death. VEGFA is the therapeutic target of bevacizumab (Avastin). 1. Katsman, M. et al. (2022) Cells 11. PMID: 35455969
Nota	For research use only. Not suitable for clinical or therapeutic use.

Imágenes

Bioactivity

Detects Human VEGFA in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Ranibizumab.

Referencias

Datasheet

Research Grade Ranibizumab.pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo