





| Каталожный номер | HV212016 |
|---|---|
| Описание |
Belimumab (HV212016) is a research-grade recombinant antibody targeting CD257. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| Реактивность видов | Human |
| Применения | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Хозяинский вид | Human |
| Изотип | IgG1-lambda |
| Система экспрессии | Mammalian Cells |
| Клоональность | Monoclonal |
| Цель | BAFF, ZTNF4, BLYS, Tumor necrosis factor ligand superfamily member 13B, Dendritic cell-derived TNF-like molecule, TALL-1, TNF- and APOL-related leukocyte expressed ligand 1, BLyS, B lymphocyte stimulator, TNFSF13B, CD257, TNFSF20, TALL1, B-cell-activating factor |
| Уровень эндотоксинов | Please contact the lab for this information. |
| Чистота | >95% purity as determined by SDS-PAGE. |
| Очистка | Protein A/G purified from cell culture supernatant. |
| Номер доступа | Q9Y275 |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS, pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Альтернативные названия | LymphoStat-B, hBlySmAb-1.1, 356547-88-1 |
| Фон | Tumor necrosis factor ligand superfamily member 13B (CD257/BAFF) is a ~31 kDa protein. Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response. |
| Примечание | For research use only. Not suitable for clinical or therapeutic use. |

SEC-HPLC detection for Research Grade Belimumab.

SDS-PAGE for Research Grade Belimumab

Western blot analysis was performed using anti-CD257/BAFF/TNFSF13B monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD257/BAFF/TNFSF13B (Catalog No: HV212011)
Lane 2: negative control




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