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Research Grade Ramucirumab (HW338016)

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Research Grade Ramucirumab

Research Grade Ramucirumab

Research Grade Ramucirumab

Research Grade Ramucirumab

Research Grade Ramucirumab

Research Grade Ramucirumab

Precio(USD): $

Especificación:

100ug
1mg

Número:

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Vista general
Imágenes
Referencias
Datasheet

Vista general

Número de catálogo	HW338016
Descripción	Ramucirumab (HW338016) is a research-grade recombinant antibody targeting CD309. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactividad de especies	Human
Aplicaciones	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Especie huésped	Human
Isotipo	IgG1-kappa
Sistema de expresión	Mammalian Cells
Clonalidad	Monoclonal
Objetivo	FLK-1, Kinase insert domain receptor, VEGFR2, Fetal liver kinase 1, CD309, Vascular endothelial growth factor receptor 2, Protein-tyrosine kinase receptor flk-1, FLK1, VEGFR-2, KDR
Nivel de endotoxinas	Please contact the lab for this information.
Pureza	>95% purity as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P35968
Forma	Liquid
Buffer de almacenamiento	0.01M PBS, pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Nombres alternativos	1121B, IMC-1121B, LY3009806, 947687-13-0
Fondo	Vascular endothelial growth factor receptor 2 (CD309/VEGFR-2) is a ~151 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain, such as isoform 2 and isoform 3, may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. CD309 is the therapeutic target of ramucirumab (Cyramza).
Nota	For research use only. Not suitable for clinical or therapeutic use.

Imágenes

SEC-HPLC

SEC-HPLC detection for Research Grade Ramucirumab.
Bioactivity

Detects Human CD309/KDR/VEGFR-2 in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Ramucirumab

Referencias

Datasheet

Research Grade Ramucirumab.pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

=

Concentration

×

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

×

V₁ (Stock Vol.)

=

Working Solution

C₂ (Working Conc.)

×

V₂ (Working Vol.)

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Research Grade Ramucirumab