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Research Grade Elotuzumab (HV217016)

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Research Grade Elotuzumab

Research Grade Elotuzumab

Research Grade Elotuzumab

Research Grade Elotuzumab

Research Grade Elotuzumab

Research Grade Elotuzumab

Prix(USD) : $

Spécification :

100ug
1mg

Nombre :

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Aperçu
Images
Reférences
Fiche technique

Aperçu

Numéro de catalogue	HV217016
Description	Elotuzumab (HV217016) is a research-grade recombinant antibody targeting CD2. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Humanized
Isotype	IgG1-kappa
Système d'expression	Mammalian Cells
Clonalité	Monoclonal
Cible	SLAMF7, CRACC, Protein 19A, SLAM family member 7, CD2-like receptor-activating cytotoxic cells, Membrane protein FOAP-12, CD319, Novel Ly9, CD2 subset 1, CS1
Niveau d'endotoxines	Please contact the lab for this information.
Pureté	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	Q9NQ25
Forme	Liquid
Tampon de stockage	0.01M PBS, pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Noms alternatifs	BMS-901608, PDL063, HuLuc63, 915296-00-3
Contexte	SLAM family member 7 (CD319/SLAMF7) is a ~37 kDa protein. Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Isoform 1 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. Positively regulates NK cell functions by a mechanism dependent on phosphorylated SH2D1B. 1. Bouchon, A. et al. (2001) Journal of immunology (Baltimore, Md. : 1950) 167, 5517-21. PMID: 11698418 2. Tassi, I. et al. (2005) Journal of immunology (Baltimore, Md. : 1950) 175, 7996-8002. PMID: 16339536 3. Murphy, JJ. et al. (2002) The Biochemical journal 361, 431-6. PMID: 11802771 4. Kim, JR. et al. (2013) Inflammation research : official journal of the European Histamine Research Society ... [et al.] 62, 765-72. PMID: 23695528
Note	For research use only. Not suitable for clinical or therapeutic use.

Images

Bioactivity

Detects Human CD319/SLAMF7 in indirect ELISAs.
Bioactivity

SEC-HPLC detection for Research Grade Elotuzumab.
SDS-PAGE

SDS-PAGE for Research Grade Elotuzumab.

Reférences

Fiche technique

Research Grade Elotuzumab.pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Formula

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Stock Solution

C₁ (Stock Conc.)

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V₁ (Stock Vol.)

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Working Solution

C₂ (Working Conc.)

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Research Grade Elotuzumab