

| Número de catálogo | HB732206 |
|---|---|
| Descripción |
gimvekibart (HB732206) is a research-grade recombinant antibody targeting CD124.
Highlights
|
| Reactividad de especies | Human |
| Aplicaciones | ELISA, FACS, Functional assay |
| Especie huésped | Human |
| Isotipo | IgG4, kappa |
| Objetivo | CD124/IL4R/IL-4Rα |
| Pureza | >95% as determined by SDS-PAGE |
| Número de acceso | P24394 |
| Buffer de almacenamiento | 0.01 M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Nombres alternativos | CAS: 3037526-90-9 |
| Fondo | Interleukin-4 receptor subunit alpha is a ~89 kDa protein. Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2. 1. Andrews, AL. et al. (2006) The Journal of allergy and clinical immunology 118, 858-65. PMID: 17030238 |
| Nota | For research use only. |

SDS-PAGE for Research Grade gimvekibart




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