Research Grade Anti-Human CD46 Antibody (FOR46) (HB735016)

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100ug
1mg

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Aperçu

Numéro de catalogue	HB735016
Description	Anti-Human CD46 Antibody (FOR46) (HB735016) is a research-grade recombinant antibody targeting CD46. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Reactivité des espèces	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Espèce hôte	Human
Isotype	IgG
ID de clone	FOR46
Système d'expression	Mammalian Cells
Cible	Trophoblast leukocyte common antigen, CD46, TLX, MCP, Membrane cofactor protein, MIC10
Niveau d'endotoxines	Please contact the lab for this information.
Pureté	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P15529
Forme	Liquid
Tampon de stockage	0.01M PBS, pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Noms alternatifs	FOR46, FOR46, FOR-46
Contexte	Membrane cofactor protein (CD46) is a ~43 kDa protein. Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity.
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for Research Grade Anti-Human CD46 Antibody (FOR46)
Bioactivity

Detects recombinant CD46 (Catalog No: HB735011) in indirect ELISA.

Reférences

Fiche technique

Research Grade Anti-Human CD46 Antibody (FOR46).pdf

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