



| Número de catálogo | HV698016 |
|---|---|
| Descripción |
Cevostamab (HV698016) is a research-grade recombinant antibody targeting CD307. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| Reactividad de especies | Human |
| Aplicaciones | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| Especie huésped | Humanized |
| Isotipo | IgG1-kappa |
| Sistema de expresión | Mammalian Cells |
| Clonalidad | Monoclonal |
| Objetivo | FcRL5, FCRH5, FCRL5, Fc receptor homolog 5, FcRH5, CD307e, FcR-like protein 5, IRTA2, Immune receptor translocation-associated protein 2, BXMAS1, Fc receptor-like protein 5, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain |
| Nivel de endotoxinas | Please contact the lab for this information. |
| Pureza | >95% purity as determined by SDS-PAGE. |
| Purificación | Protein A/G purified from cell culture supernatant. |
| Número de acceso | Q96RD9 & P07766 |
| Forma | Liquid |
| Buffer de almacenamiento | 0.01M PBS, pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| Nombres alternativos | Bispecific, BFCR-4350-A, BFCR-4350A, RG-6160, RO-7187797, 2249888-53-5 |
| Fondo | Cevostamab (BFCR4350A; RG6160; RO7187797) is a humanized IgG1-based BsAb that targets membrane-proximal extracellular domain of FcRH5 on multiple myeloma (MM) cells as well as CD3 on T cells. Moreover, Cevostamab facilitates efficient synapse formation, improves killing activity of T cells against MM tumor cells. |
| Nota | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for Research Grade Cevostamab.

SEC-HPLC detection for Research Grade Cevostamab.
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