

| Каталожный номер | HP116014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human RAB1B (Met1-Gly176). | ||||||||
| Цель | RAB1B, Ras-related protein Rab-1B | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | Q9H0U4 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Ras-related protein Rab-1B (RAB1B) is a ~22 kDa protein. The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Plays a role in the initial events of the autophagic vacuole development which take place at specialized regions of the endoplasmic reticulum. Regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments. Required to modulate the compacted morphology of the Golgi. 1. Zoppino, FC. et al. (2010) Traffic (Copenhagen, Denmark) 11, 1246-61. PMID: 20545908 2. Overmeyer, JH. et al. (1998) Molecular biology of the cell 9, 223-35. PMID: 9437002 3. Gavriljuk, K. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, 21348-53. PMID: 23236136 4. Aizawa, M. et al. (2015) The Journal of biological chemistry 290, 22250-61. PMID: 26209634 | ||||||||
| Примечание | For research use only. |
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