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Timely TGFβ signalling inhibition induces notochord

10.1038/s41586-024-08332-w

Affiliations
Tiago Rito, Ashley R G Libby, Madeleine Demuth, Marie-Charlotte Domart, Jake Cornwall-Scoones, James Briscoe

DOI: 10.1038/s41586-024-08332-w

Abstract
The formation of the vertebrate body involves the coordinated production of trunk tissues from progenitors located in the posterior of the embryo. Although in vitro models using pluripotent stem cells replicate aspects of this process

Keywords
TGF-β，notochord

Связанные продукты

Каталожный номер	Название продукта	Описание	Цель
HF977096	TGF-β	Anti-Human TGFB1/TGF-beta-1 (SRK-181) (HF977096) is a research-grade recombinant antibody targeting Transforming growth factor beta-1 proprotein. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.	Transforming growth factor beta-1 proprotein, LAP, TGF-beta-1, TGFB1, TGFB