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| カタログ番号 | VK535014 | ||||||||
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| 説明 |
Anti-CHPV M/Matrix protein Polyclonal Antibody (VK535014) is a rabbit polyclonal antibody detecting Matrix protein in ELISA, IHC, WB.
Highlights
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| 種反応性 | Chandipura virus (strain I653514) (CHPV) | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| アイソタイプ | IgG | ||||||||
| クローン性 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Chandipura virus (CHPV) M/Matrix protein (Phe47-His229). | ||||||||
| ターゲット | Matrix protein, M | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9WH76 | ||||||||
| RRID | Anti-CHPV M/Matrix protein Polyclonal Antibody (abinScience Cat# VK535014, RRID:AB_3725149) |
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| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Matrix protein is a ~26 kDa protein. Forms a double layer around the helical nucleocapsid, the inner matrix layer binding to the N helix and the outer matrix layer binding to the envelope glycoprotein. Plays a major role in assembly and budding of virion, by recruiting cellular partners of the ESCRT complexes that play a key role in releasing the budding particle from the host membrane. Condensates the ribonucleocapsid core during virus assembly. Inhibits the host mRNA nuclear export thereby inducing the shut off of cellular transcription and preventing the interferon signaling and the establishment of antiviral state in infected cells. This shutoff presumably inhibits interferon signaling and thus establishment of antiviral state in virus infected cells. | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-Matrix-CHPV polyclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant CHPV M/Matrix protein (Catalog No: VK535012)
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