

| Número de catálogo | VK521024 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Fusion Protein Polyclonal Antibody (VK521024) is a rabbit polyclonal antibody detecting fusion; F in ELISA, IHC, WB. Suitable for Nipah virus and Hendra virus.
Highlights
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| Reactividad de especies | Nipah virus, Hendra virus | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Isotipo | IgG | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Inmunógeno | E. coli - derived recombinant hendra virus Fusion (Ile27-Ser487). | ||||||||
| Objetivo | fusion; F | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | O89342, Q9IH63 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Fusion glycoprotein F0 is a ~59 kDa protein. Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm. | ||||||||
| Nota | For research use only |



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