Anti-HeV/NiV F/Fusion glycoprotein F0 Antibody (1F5) (VK431033)

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1mg

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Datasheet

Vista general

Número de catálogo

VK431033

Descripción

Anti-HeV/NiV F/Fusion glycoprotein F0 Antibody (1F5) [1F5] (VK431033) is a mouse monoclonal antibody detecting Fusion glycoprotein F0 in ELISA, Neutralization.

Reactividad de especies

Hendra virus (isolate Horse/Autralia/Hendra/1994) & Nipah virus

Aplicaciones

ELISA, Neutralization

Especie huésped

Mouse

Isotipo

IgG1, kappa

ID de clon

1F5

Clonalidad

Monoclonal

Objetivo

F, Fusion glycoprotein F0, Protein F

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

O89342, Q9IH63

RRID

Anti-HeV/NiV F/Fusion glycoprotein F0 Antibody (1F5) (abinScience Cat# VK431033, RRID:AB_3725240)

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Fusion glycoprotein F0 is a ~59 kDa protein. Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm.

Nota

For research use only.

Imágenes

Bioactivity

SEC-HPLC detection for Anti-HeV/NiV F/Fusion glycoprotein F0 Antibody (1F5).
SDS-PAGE

SDS-PAGE for Anti-HeV/NiV F/Fusion glycoprotein F0 Antibody (1F5).