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| カタログ番号 | VK500094 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Protein 3A Polyclonal Antibody (VK500094) is a rabbit polyclonal antibody detecting Protein 3A in ELISA, IHC, WB.
Highlights
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| 種反応性 | Foot-and-mouth disease virus (FMDV) | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| アイソタイプ | IgG | ||||||||
| クローン性 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Genome polyprotein (Glu1503-Glu1578). | ||||||||
| ターゲット | Genome polyprotein, Leader protease, Lpro, EC:3.4.22.46, Capsid protein VP0, VP4-VP2, Capsid protein VP4, P1A, Virion protein 4, Capsid protein VP2, P1B, Virion protein 2, Capsid protein VP3, P1C, Virion protein 3, Capsid protein VP1, P1D, Virion protein 1, Protein 2A, P2A, P52, Protein 2B, P2B, Protein 2C, P2C, EC:3.6.1.15, Protein 3A, P3A, Protein 3B-1, P3B-1, Genome-linked protein VPg1, Protein 3B-2, P3B-2, Genome-linked protein VPg2, Protein 3B-3, P3B-3, Genome-linked protein VPg3, Protease 3C, EC:3.4.22.28, Picornain 3C, P3C, Protease P20B, RNA-directed RNA polymerase 3D-POL, P3D-POL, EC:2.7.7.48, P56A | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P03307 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Genome polyprotein (Protein 3A) is a ~259 kDa protein. Autocatalytically cleaves itself from the polyprotein at the L/VP0 junction. Also cleaves the host translation initiation factors EIF4G1 and EIF4G3, in order to shut off the capped cellular mRNA transcription. Plays a role in counteracting host innate antiviral response using diverse mechanisms. Possesses a deubiquitinase activity acting on both 'Lys-48' and 'Lys-63'-linked polyubiquitin chains. In turn, inhibits the ubiquitination and subsequent activation of key signaling molecules of type I IFN response such as host RIGI, TBK1, TRAF3 and TRAF6. | ||||||||
| 注意事項 | For research use only |
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