



| Каталожный номер | AF998043 |
|---|---|
| Описание |
Anti-Ibalizumab Neutralizing Recombinant Antibody (SAA2978) (AF998043) is a mouse monoclonal antibody detecting Ibalizumab in ELISA. Suitable for General.
Highlights
|
| Реактивность видов | General |
| Применения | ELISA |
| Хозяинский вид | Mouse |
| Клоональность | Monoclonal |
| Изотип | IgG1 |
| ID клона | SAA2978 |
| Иммуноген | Ibalizumab |
| Уровень эндотоксинов | < 10EU/mg |
| Чистота | >95% as determined by SDS-PAGE. |
| Очистка | Protein A/G purified from cell culture supernatant. |
| Номер доступа | CAS: 680188-33-4 |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Фон | T-cell surface glycoprotein CD4 (Ibalizumab) is a ~51 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. |
| Примечание | For research use only. |

Detects Ibalizumab in indirect ELISA.

Blocks the binding of Ibalizumab to CD4.



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