

| Каталожный номер | HV191013 |
|---|---|
| Описание |
Anti-Human CD180 Recombinant Antibody (ABB071) (HV191013) is a human monoclonal antibody detecting CD180 in ELISA, FCM, Functional assay. Suitable for Human.
Highlights
|
| Реактивность видов | Human |
| Применения | ELISA, FCM, Functional assay |
| Хозяинский вид | Human |
| Клоональность | Monoclonal |
| Изотип | IgG1, kappa |
| ID клона | ABB071 |
| Цель | CD180, CD180 antigen, LY64, Lymphocyte antigen 64, RP105, Radioprotective 105 kDa protein |
| Уровень эндотоксинов | < 10 EU/mg as determined by LAL method. |
| Чистота | >95% as determined by SDS-PAGE. |
| Очистка | Protein A/G purified from cell culture supernatant. |
| Номер доступа | Q99467 |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Фон | CD180 antigen is a ~74 kDa protein. Pattern recognition receptor predominantly expressed on B-cells, dendritic cells, and certain monocytes/macrophages, structurally resembling Toll-like receptors (TLRs) that plays a role in modulating immune responses. While ressembling a TLR, lacks the intracellular TIR (Toll/IL-1R) signaling domain and thus does not directly transduce signals. Instead, modulates immune responses, often in conjunction with other TLRs. For example, in cooperation with MD-1/LY86, interacts directly with the TLR4 signaling complex, inhibiting its ability to bind microbial ligand. 1. Divanovic, S. et al. (2005) Nature immunology 6, 571-8. PMID: 15852007 |
| Примечание | For research use only. |




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