Anti-Mouse Integrin beta 3/CD61 Polyclonal Antibody (MY323014)

Name: Anti-Mouse Integrin beta 3/CD61 Polyclonal Antibody
Brand: abinScience
SKU: MY323014
Price: 168 USD
Availability: InStock

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Referencias
Datasheet
SDS

Vista general

Número de catálogo

MY323014

Descripción

Anti-Mouse Integrin beta 3/CD61 Polyclonal Antibody (MY323014) is a rabbit polyclonal antibody detecting Integrin beta 3/CD61 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactividad de especies

Human, Mouse, Rat

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Mouse CD61/ITGB3 (Pro136-Ser378).

Objetivo

CD61, GP3A, GPIIIa, ITGB3, Integrin beta-3, Platelet membrane glycoprotein IIIa

Nivel de endotoxinas

Please contact with the lab for this information.

Purificación

Purified by antigen affinity column.

Número de acceso

O54890

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Fondo

Integrin beta-3 (Integrin αVβ3 (CD51/ITGAV & CD61) is a ~87 kDa protein. Integrin alpha-V/beta-3 (ITGAV:ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 (ITGA2B:ITGB3) is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen.

1. Si-Tahar, M. et al. (1997) The Journal of biological chemistry 272, 11636-47. PMID: 9111081

2. Fujita, M. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 189, 5809-19. PMID: 23125415

3. Fujita, M. et al. (2014) PloS one 9, e96372. PMID: 24789099

4. Ieguchi, K. et al. (2010) The Journal of biological chemistry 285, 31388-98. PMID: 20682778

5. Mori, S. et al. (2008) The Journal of biological chemistry 283, 18066-75. PMID: 18441324

6. Mori, S. et al. (2017) Bioscience reports 37. PMID: 28302677

7. Saegusa, J. et al. (2009) The Journal of biological chemistry 284, 24106-14. PMID: 19578119

8. Cedano Prieto, DM. et al. (2017) PloS one 12, e0184285. PMID: 28873464

9. Takada, YK. et al. (2017) The Journal of biological chemistry 292, 20067-20075. PMID: 29030430

10. Saegusa, J. et al. (2008) The Journal of biological chemistry 283, 26107-15. PMID: 18635536

Nota

For research use only

Imágenes

Referencias

Datasheet

Anti-Mouse Integrin beta 3/CD61 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

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