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Anti-Mouse SREBF1/SREBP1 Polyclonal Antibody (MW748014)

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Aperçu
Numéro de catalogueMW748014
Description
Anti-Mouse SREBF1/SREBP1 Polyclonal Antibody (MW748014) is a rabbit polyclonal antibody detecting SREBF1/SREBP1 in ELISA, IHC, WB. Suitable for Mouse, Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesMouse, Rat
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant Mouse SREBF1/SREBP1 (Gly566-Gly1126).
Cible BHLHD1, Class D basic helix-loop-helix protein 1, Processed sterol regulatory element-binding protein 1, SREBF1, SREBP-1, SREBP1, Sterol regulatory element-binding protein 1, Sterol regulatory element-binding transcription factor 1, Transcription factor SREBF1, bHLHd1
Niveau d'endotoxines Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Numéro d'accès Q9WTN3
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Contexte

Sterol regulatory element-binding protein 1 (SREBF1/SREBP1) is a ~121 kDa protein. Precursor of the transcription factor form (Processed sterol regulatory element-binding protein 1), which is embedded in the endoplasmic reticulum membrane. Low sterol concentrations promote processing of this form, releasing the transcription factor form that translocates into the nucleus and activates transcription of genes involved in cholesterol biosynthesis and lipid homeostasis.

1. Xu, D. et al. (2020) Nature 580, 530-535. PMID: 32322062
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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