Anti-African clawed frog IRF7 Polyclonal Antibody (ZD620014)

Name: Anti-African clawed frog IRF7 Polyclonal Antibody
Brand: abinScience
SKU: ZD620014
Price: 168 USD
Availability: InStock

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Precio(USD): --

Especificación:

50ug
100ug

Número:

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Número de catálogo

ZD620014

Descripción

Anti-African clawed frog IRF7 Polyclonal Antibody (ZD620014) is a rabbit polyclonal antibody detecting IRF7 in ELISA, IHC, WB. Suitable for Xenopus laevis (African clawed frog).

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactividad de especies

Xenopus laevis (African clawed frog)

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant African clawed frog IRF7 (Met1-Pro127).

Objetivo

IRF-7, IRF7, Interferon regulatory factor 7

Nivel de endotoxinas

Please contact with the lab for this information.

Purificación

Purified by antigen affinity column.

Número de acceso

A0A1L8GJP7

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Fondo

Interferon regulatory factor 7 is a ~54 kDa protein. Key transcriptional regulator of type I interferon (IFN)-dependent immune responses and plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. Can efficiently activate both the IFN-beta (IFNB) and the IFN-alpha (IFNA) genes and mediate their induction via both the virus-activated, MyD88-independent pathway and the TLR-activated, MyD88-dependent pathway. Induces transcription of ubiquitin hydrolase USP25 mRNA in response to lipopolysaccharide (LPS) or viral infection in a type I IFN-dependent manner. Required during both the early and late phases of the IFN gene induction but is more critical for the late than for the early phase.

1. Hwang, SW. et al. (2017) Biochemical and biophysical research communications 486, 700-705. PMID: 28342865

2. Kitagawa, Y. et al. (2017) Journal of virology 91. PMID: 28768858

3. Panne, D. et al. (2007) Cell 129, 1111-23. PMID: 17574024

4. Zhang, Q. et al. (2020) Science (New York, N.Y.) 370. PMID: 32972995

5. Marié, I. et al. (2000) Molecular and cellular biology 20, 8803-14. PMID: 11073981

6. Caillaud, A. et al. (2002) The Journal of biological chemistry 277, 49417-21. PMID: 12374802

7. Kawai, T. et al. (2004) Nature immunology 5, 1061-8. PMID: 15361868

8. Sgarbanti, M. et al. (2007) Annals of the New York Academy of Sciences 1095, 325-33. PMID: 17404045

Nota

For research use only

Imágenes

Referencias

Datasheet

Anti-African clawed frog IRF7 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo

Anti-African clawed frog IRF7 Polyclonal Antibody (ZD620014)

Vista general

Imágenes

Referencias

Datasheet

SDS